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KMID : 0359320230630020010
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Korean Journal of Veterinary Research
2023 Volume.63 No. 2 p.10 ~ p.10
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Successful long-term management of late-stage precursor-targeted immune-mediated anemia with prednisolone and mycophenolate mofetil in a dog
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Kim Do-Yun
Lee Seong-Pyo
Kim Sung-Soo
Jeong So-Young
Hong Hyun-Jeong
Yun Young-Min
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Abstract
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A 13-year-old neutered male Maltese dog presented to our hospital with lethargy and anorexia. Laboratory abnormalities included severe non-regenerative anemia (hematocrit, 12.9%; reticulocyte count 12.8 K/μL). The cytology of bone marrow revealed erythroid hypercellularity with mild myelofibrosis. Therefore, late-stage precursor-targeted immune-mediated anemia (PIMA) was diagnosed. Multimodal treatment including 2 immunosuppressant drugs (prednisolone and mycophenolate mofetil), antithrombic drug (clopidogrel), and blood transfusion was performed. The dog showed complete remission from PIMA, and the total duration of follow-up was 622 days. This is the first case report of canine PIMA managed successfully with prednisolone and mycophenolate mofetil in Korea.
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KEYWORD
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anemia, bone marrow examination, dogs, immunosuppressive agents
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